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Computational Metabolomics
& Systems Biology to Drive
Fundamental Discovery











About



The Metsys Lab is part of the Department of Electrical, Electronic and Control Engineering at the University Rovira i Virgili (URV), and the Omics Sciences Unit at The Technology Centre of Catalonia (EURECAT). We combine bioinformatics and analytical chemistry to develop computational tools applied to mass spectrometry-based metabolomics.

Computational metabolomics

Metabolites are the downstream product of cellular biochemistry. At the same time, metabolites are the central hub in microbiome-host interactions. The identification (annotation) of metabolites in biomedical experiments is the cornerstone for gaining new insights into cell biology, physiology and medicine. Mass spectrometry-based metabolomics is a widely used technique that allows measuring metabolites in biofluids and tissues from living organisms. At the Metsys lab we combine signal processing, machine learning, statistical and analytical chemistry techniques to develop bioinformatics tools and resources for mass spectrometry-based metabolomics data analysis and metabolite identification.


Our lab is or has been supported by:

Research

Our lab works at the intersection between different disciplines...


SIGNAL PROCESSING

MACHINE LEARNING

ANALYTICAL CHEMISTRY

To process mass spectrometry signals and leverage their multivariate nature to enhance data processing performance. To predict chemical properties or analyze complex molecular interactions. To increase the algorithm's performance by designing specific analytical solutions and methods.

SYSTEMS BIOLOGY

STATISTICS

To understand complex biological interactions through multi-omics data integration. To make our methods robust and assess the accuracy of our algorithms and biological findings.

... applying them for fundamental discovery in metabolomics research:


with the following overarching research aims:


- Design methods and tools for metabolite annotation and identification

- High-throughput metabolomics data processing algorithm development

- Systems Biology-based molecular mechanism elucidation

THE TEAM

Now hiring!

We are looking for a motivated PhD student: Position post.

Author image

Xavier Domingo-Almenara, Ph.D

Principal Investigator
  • Associate Professor, University Rovira i Virgili, Tarragona, Catalonia, Spain (2025-)
  • Adjunct Senior Researcher, Center for Omics Sciences, EURECAT, Reus, Catalonia, Spain (2025-)
  • "La Caixa" Junior Leader, EURECAT, Barcelona, Catalonia, Spain (2021-2024)
  • Adjunct Professor, University Rovira i Virgili, Tarragona, Catalonia, Spain (2019-2024)
  • Postdoctoral Researcher, Scripps Research, La Jolla, California, US (2017-2019)
  • PhD in Bioengineering, Universitat Rovira i Virgili, Tarragona, Catalonia, Spain (2016)
Author image

Aleksandr (Alex) Zubov

PhD candidate
  • Data and Research Scientist in the industry (2017-2023)
  • Master’s Degree with honors (Chemistry), Peoples' Friendship University of Russia, Moscow, Russia (2015)
  • Bachelor's Degree (Chemistry), Peoples' Friendship University of Russia, Moscow, Russia (2013)

Past members

- Trisha Arora.
PhD student (2022-2025)
- Sara M. de Cripán.
PhD student (2021-2024)
- Melanie Garvizu.
BSc student (2024)
- Pau Orts.
BSc student (2024)
- Júlia Vall.
BSc student (2023)
- Pedro M. López Zarzuela.
Staff Bioinformatics Scientist (2022)
- Adrià Olomí.
BSc student (2022)

PUBLICATIONS

(Selected)